Περίληψη:
Background Studies have suggested that risk of leukemia may be
associated with occupational or industrial exposures and risk may vary
by the histological type of the disease.
Methods A population-based case-control study was conducted in Iowa and
Minnesota to evaluate the association between various occupations,
industries, and occupational exposures and leukemia risk. A total of 513
cases and 1,087 controls was included in the study. A lifetime
occupational history and other risk factor information were collected
through in-person interviews, and a job-exposure matrix was used to
assess possible risks associated with specific exposures.
Results A significantly increased risk of leukemia was observed among
agricultural service industries and among nursing and healthcare
workers. Janitors, cleaners, and light truck drivers also experienced
increased risk. Those employed in plumbing, heating and air conditioning
industries, and sales of nondurable goods (such as paints and varnishes)
had an increased risk. Printers, painters, and workers in the food and
metal industries had a nonsignificantly increased risk of leukemia.
Analyses by specific exposures and histology of leukemia showed that
risk of leukemia associated with occupational or industrial exposures
may vary by histological type of the disease.
Conclusions An increased risk of leukemia among workers employed in
agricultural industries, nursing and healthcare workers, and in a few
occupations with possible exposure to solvents is consistent with
earlier studies. Associations of risk with occupations not observed
previously deserve further assessment. Published 2001 Wiley-Liss,
Inc.(dagger).
Συγγραφείς:
Blair, A
Zheng, T
Linos, A
Stewart, PA
Zhang, YW and
Cantor, KP
