Περίληψη:
The aim of this population-based prospective study was to determine the
incidence of limb fracture by site and gender in different regions of
Europe. Men and women aged 50-79 years were recruited from population
registers in 31 European centers. Subjects were invited to attend for an
interviewer-administered questionnaire and lateral spinal radiographs.
Subjects were subsequently followed up using an annual postal
questionnaire which included questions concerning the occurrence of new
fractures. Self-reported fractures were confirmed where possible by
radiograph, attending physician or subject interview. There were 6451
men and 6936 women followed for a median of 3.0 years. During this time
there were 140 incident limb fractures in men and 391 in women. The
age-adjusted incidence of any limb fracture was 7,3/1000 person-years
[pyrs] in men and 19 per 1000 pyrs in women, equivalent to a 2,5 times
excess in women. Among women, the incidence of hip, humerus and distal
forearm fracture, though not ‘other’ limb fracture, increased with age,
while in men only the incidence of hip and humerus fracture increased
with age. Among women, there was evidence of significant variation in
the occurrence of hip, distal forearm and humerus fractures across
Europe, with incidence rates higher in Scandinavia than in other
European regions. though for distal forearm fracture the incidence in
east Europe was similar to that observed in Scandinavia. Among men,
there was no evidence of significant geographic variation in the
occurrence of these fractures. This is the first large population-based
study to characterize the incidence of limb fracture in men and women
over 50 years of age across Europe. There are substantial differences in
the descriptive epidemiology of limb fracture by region and gender.
Συγγραφείς:
Ismail, AA
Pye, SR
Cockerill, WC
Lunt, M
Silman, AJ and
Reeve, J
Banzer, D
Benevolenskaya, LI
Bhalla, A
Armas,
JB
Cannata, JB
Cooper, C
Delmas, PD
Dequeker, J and
Dilsen, G
Falch, JA
Felsch, B
Felsenberg, D
Finn, JD and
Gennari, C
Hoszowski, K
Jajic, I
Janott, J
Johnell, O
and Kanis, JA
Kragl, G
Vaz, AL
Lorenc, R
Lyritis, G and
Marchand, F
Masaryk, P
Matthis, C
Miazgowski, T and
Naves-Diaz, M
Pols, HAP
Poor, G
Rapado, A
Raspe, HH and
Reid, DM
Reisinger, W
Scheidt-Nave, C
Stepan, J
Todd, C
and Weber, K
Woolf, AD
O'Neill, TW
