Τίτλος:
Cytomegalovirus as a cause of anterior uveitis with sectoral iris
atrophy
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objective: To report two cases of recurrent anterior uveitis with
sectoral iris atrophy and ocular hypertension during attacks caused by
cytomegalovirus (CMV).
Design: Two observational case reports.
Participants: Two immunocompetent patients with a history of recurrent
unilateral hypertensive anterior uveitis with sectoral iris atrophy were
referred to us with the presumptive diagnosis of herpetic uveitis.
Main Outcome Measures: Comprehensive ophthalmic examination, aqueous
humor polymerase chain reaction (PCR), and peripheral blood serologic
studies were performed on both patients.
Results: Examination of aqueous humor by PCR was positive for CMV and
negative for herpesvirus. Serum IgG/IgM titers disclosed past CMV
infection. Both patients responded well to antiviral therapy with
ganciclovir. The final visual acuity level was 20/20 in both eyes of
both patients.
Conclusions: CMV infection can produce recurrent attacks of anterior
uveitis with clinical characteristics indistinguishable from those
previously considered highly suggestive or even pathognomonic for
herpetic infection. This observation has implications for the
therapeutic management of such patients. Ophthalmology 2002;109:879-882
(C) 2002 by the American Academy of Ophthalmology.
Συγγραφείς:
Markomichelakis, NN
Canakis, C
Zafirakis, P
Marakis, T and
Mallias, I
Theodossiadis, G
Περιοδικό:
Ophthalmology Management
Εκδότης:
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
DOI:
10.1016/S0161-6420(02)00961-2
