Τίτλος:
Dietary and lifestyle factors in relation to plasma insulin-like growth
factor I in a general population sample
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
There is evidence that the insulin-like growth factor system (IGF),
particularly IGF-I, is important in human carcinogenesis. We studied in
a general, though not strictly random population sample of 620 adults,
the relationship of IGF-I to demographic, lifestyle and dietary factors,
the latter ascertained through an extensive validated questionnaire.
Plasma IGF-I levels declined significantly with age and the decline was
more evident among women than among men. Tobacco smoking, body mass
index and regular physical activity were unrelated to this hormone and a
positive association with height was not statistically significant
Neither protein nor carbohydrate intake was related to plasma IGF-I
levels but there was inconsistent evidence that ethanol intake may be
inversely associated with plasma IGF-I and saturated and polyunsaturated
lipids may be positively associated with it. The findings are evaluated
in conjunction with evidence indicating that the incidence of cancer is
lower among women than among men, height is a risk factor for several
forms of cancer, and saturated and polyunsaturated lipids have been more
closely linked to human and animal carcinogenesis than monounsaturated
lipids. (C) 2003 Lippincott Williams Wilkins.
Συγγραφείς:
Baibas, N
Bamia, C
Vassilopoulou, E
Sdrolias, J and
Trichopoulou, A
Trichopoulos, D
Περιοδικό:
European Journal of Cancer Prevention: The Official Journal of the European Cancer Prevention Organisation (ECP)
Εκδότης:
Lippincott, Williams & Wilkins
Λέξεις-κλειδιά:
diet; dietary lipids; ethanol; IGF-1; IGFBP-3; smoking
DOI:
10.1097/00008469-200306000-00010
