Τίτλος:
Vitamin D in acutely ill patients
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objective: To investigate 25(OH)D3 levels and their relationship to survival in a cohort of acutely ill patients on admission to an intensive care unit. Methods: This study enrolled acutely ill patients at admission to an intensive care unit and a group of sex- and age-matched healthy control subjects. The 25(OH)D3 levels were measured using an enzyme immunoassay. C-reactive protein and procalcitonin levels were also measured using immunoassays. Results: A total of 50 acutely ill patients and 50 healthy control subjects were enrolled in the study. The mean ± SEM 25(OH)D3 levels were significantly lower in the acutely ill patients compared with the control group (11.74 ± 0.88 ng/ml versus 24.66 ± 1.60 ng/ml, respectively). The 25(OH)D3 levels were not related to survival. An inverse relationship was observed between 25(OH)D3 levels and C-reactive protein levels. A weak inverse relationship was also observed between 25(OH)D3 levels and procalcitonin levels. Conclusions: The 25(OH)D3 levels were decreased in acutely ill patients admitted to an intensive care unit compared with healthy control subjects. 25(OH)D3 levels may be inversely related to C-reactive protein and procalcitonin levels. © The Author(s) 2018.
Συγγραφείς:
Kostoglou-Athanassiou, I.
Pantazi, E.
Kontogiannis, S.
Kousouris, D.
Mavropoulos, I.
Athanassiou, P.
Περιοδικό:
Journal of International Medical Research
Εκδότης:
SAGE Publications Ltd
Λέξεις-κλειδιά:
C reactive protein; calcifediol; procalcitonin; C reactive protein; calcifediol; calcitonin, adult; aged; Article; clinical article; cohort analysis; controlled study; critical illness; critically ill patient; enzyme immunoassay; female; hormone blood level; hospital admission; human; intensive care unit; male; middle aged; prospective study; protein blood level; very elderly; vitamin blood level; acute disease; blood; deficiency; mortality; statistics and numerical data; vitamin D deficiency; young adult, Acute Disease; Adult; Aged; Aged, 80 and over; C-Reactive Protein; Calcifediol; Calcitonin; Critical Illness; Female; Humans; Intensive Care Units; Male; Middle Aged; Prospective Studies; Vitamin D Deficiency; Young Adult
DOI:
10.1177/0300060518792783
