Τίτλος:
Depression in choroidal melanoma patients treated with proton beam radiotherapy
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Aim: To determine depression in patients with choroidal melanoma (CM) treated with proton beam radiotherapy. Patients and Methods: This was a cross-sectional study including 50 patients with CM (50% males, mean age=49.88±6.34 years) and 46 age- and sex-matched healthy controls (52% males, mean age=48.60±8.05 years). Participants completed the Patient Health Questionnaire-9 (PHQ-9) and the Zung Self-Rating Depression Scale (SDS) questionnaires. Results: There was a considerable difference in visual acuity as logarithm of the minimum angle of resolution (logMAR) between the patient and control groups (1.16±0.97 and 0.04±0.05 logMAR, respectively, p<0.0001). Both PHQ-9 and SDS scores differed significantly between the two groups (10.18±4.68 and 8.07±4.90, p=0.04; and 47.94±12.56 and 39.91±8.80, p=0.004, respectively). Scores appeared to be positively correlated with logMAR visual acuity (Spearman rho=0.700, p<0.0001 for PHQ-9; and 0.767, p<0.0001 for SDS), and they were also correlated to each other (Spearman rho=0.759, p<0.0001). Conclusion: Patients with CM having undergone proton beam therapy seem to be more depressed compared to a sample of healthy individuals, and the level of depression is correlated with their visual acuity. © 2018 International Institute of Anticancer Research. All rights reserved.
Συγγραφείς:
Moschos, M.M.
Moustafa, G.A.
Lavaris, A.
Damaskos, C.
Laios, K.
Karathanou, E.
Ladas, D.S.
Asproudis, I.
Garmpis, N.
Kalogeropoulos, C.
Περιοδικό:
ANTICANCER RESEARCH
Εκδότης:
International Institute of Anticancer Research
Λέξεις-κλειδιά:
adult; Article; best corrected visual acuity; cancer radiotherapy; choroid melanoma; clinical article; controlled study; cross-sectional study; depression; disease severity; female; human; male; Patient Health Questionnaire 9; priority journal; proton therapy; Zung Self Rating Depression Scale; aged; choroid tumor; depression; melanoma; middle aged; proton therapy; psychology; uvea tumor, Adult; Aged; Choroid Neoplasms; Cross-Sectional Studies; Depression; Female; Humans; Male; Melanoma; Middle Aged; Proton Therapy; Uveal Neoplasms
DOI:
10.21873/anticanres.12562
