Τίτλος:
Cognitive development of 12 month old Greek infants conceived after ICSI
and the effects of the method on their parents
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
BACKGROUND: ICSI is widely used as a method of assisted reproduction in
Greece. Research shows that children conceived after the application of
ICSI develop normally. However, Bowen et al. (1998) reported that
children conceived after ICSI had lower scores in the Mental Development
Index (MDI) of the Bayley Scales of Infant Development compared with
infants conceived naturally or by standard IVF treatment. This finding
raised concerns about the effects of ICSI on infants’ cognitive
development. The aim of the present study was twofold. First to compare
the cognitive development of Greek infants conceived after ICSI
treatment to a control group of infants conceived after IVF treatment
and to a further control group conceived naturally (NC). Second, to
investigate the psychological effects of ICSI compared to IVF on Greek
parents. METHODS: The Bayley Scales of Infant Development were employed
to assess cognitive development of infants. A 37 item semi-structured
interview was devised to obtain demographic information and to assess
and compare the psychological effects of ICSI and IVF on parents.
RESULTS: The mental development of infants in all three groups was
within the normal range (ICSI 101.4, IVF 95.7, NC 98.9). The differences
between the three groups were not statistically significant. The
duration of pregnancy and the birthweight differed in the three groups.
Furthermore, mothers in the IVF and the ICSI groups experienced anxiety
during pregnancy. IVF mothers differed in the mode of delivery and a
smaller number of these mothers breastfed their infants. CONCLUSIONS:
This study has shown that Greek infants, born after the application of
ICSI, have mental and motor scores within the normal range. With regard
to the psychological effects, it appears that mothers in the ICSI and
IVF groups experience greater anxiety during their pregnancies than
those in the NC group.
Συγγραφείς:
Papaligoura, Z
Panopoulou-Maratou, O
Solman, M
Arvaniti, K
and Sarafidou, J
Περιοδικό:
MOLECULAR HUMAN REPRODUCTION
Εκδότης:
Oxford University Press
Λέξεις-κλειδιά:
cognitive development; ICSI; IVF; psychological effects
DOI:
10.1093/humrep/deh270
