Τίτλος:
Misoprostol for second trimester pregnancy termination in women with
prior caesarean section
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objective To examine whether a previous caesarean section increases the
risk for complications in women undergoing a mid-trimester pregnancy
termination by labour induction.
Design Retrospective analysis of case records between 1997 and 2002.
Setting Fetal Medicine Unit of a large teaching hospital.
Population One hundred and eight women with a previous caesarean section
( study group) and 216 women without such a history ( controls), who
underwent a second trimester termination of pregnancy.
Methods All the terminations were performed between 17 and 24 weeks of
gestation by using 400 mug of oral administration of misoprostol in
combination with 400 mug of intravaginal misoprostol. The same dose of
intravaginal misoprostol was repeated every 6 hours for a maximum of
five doses.
Main outcome measures Severe haemorrhage requiring blood transfusion,
post-abortal infection, retained placenta and uterine rupture.
Result Complications occurred in 16 out of 108 women of the study group
(15%) and in 26 out of 216 of the controls (12%), with only one
ruptured uterus in the control group.
Conclusion We found no evidence that a previous caesarean delivery
affects the incidence of complications when women with such a history
undergo a mid-trimester pregnancy termination with misoprostol.
Συγγραφείς:
Daskalakis, GJ
Mesogitis, SA
Papantoniou, NE
Moulopoulos, GG
and Papapanagiotou, AA
Antsaklis, AJ
Περιοδικό:
BJOG: An International Journal of Obstetrics and Gynaecology
Εκδότης:
Wiley-Blackwell Publishing Ltd
DOI:
10.1111/j.1471-0528.2004.00285.x
