Τίτλος:
Sleep apnea-related cognitive deficits and intelligence: an implication
of cognitive reserve theory
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Cognitive deficits in patients with obstructive sleep apnea syndrome
(OSAS) are well demonstrated, but the pathophysiology of these deficits
is still controversial, as the relationship between OSA severity and
cognitive deficits is usually weak. Our study considers the possible
relationship between OSA-related cognitive deficits and the overall
intellectual function of OSA patients. Forty-seven OSA patients and 36
normal individuals underwent a neuropsychological battery test assessing
attention and alertness. According to the resulting IQ score, patients
and controls were divided into a high-intelligence group (IQ greater
than or equal to 90th percentile) and a normal-intelligence group (50
less than or equal to IQ < 90%ile). Between the two patient groups
there were no significant differences noticed, regarding OSA severity or
sleepiness. High-intelligence patients showed the same
attention/alertness performance compared with the high-intelligence
controls. On the contrary, patients with normal-intelligence showed
attention/alertness decline compared with the normal-intelligence
control group. The two patient groups were re-examined with the same
battery test after at least 1 year of CPAP treatment. At re-examination
neither patient group showed any differences regarding attention and
alertness compared with the control groups. We assume that
high-intelligence may have a protective effect against OSA-related
cognitive decline, perhaps due to increased cognitive reserve.
Συγγραφείς:
Alchanatis, M
Zias, N
Deligiorgis, N
Amfilochiou, A and
Dionellis, G
Orphanidou, D
Περιοδικό:
Journal of Sleep Research
Λέξεις-κλειδιά:
cognitive function; intelligence; IQ; obstructive sleep apnea syndrome
DOI:
10.1111/j.1365-2869.2004.00436.x
