Περίληψη:
xThe transmission of HIV and the progression of HIV disease are
influenced not only by a large number of human host factors, but also by
certain correlates of the ever fluctuating virus quasispecies. The
present review article aims at providing the current state of knowledge
as well as an in-depth critical discussion of recent developments on the
potential effects of HIV subtype, phenotype and attenuation on HIV
disease. Despite the extensive research, several questions regarding the
precise role that each of these correlates plays in human AIDS
pathogenesis remain unanswered. Unraveling these roles is expected to
aid the continued quest for truly effective antiretroviral drug regimens
and preventive vaccines.
