Τίτλος:
Outbreaks in distinct regions due to a single Klebsiella pneumoniae
clone carrying a bla(VIM-1) metallo-beta-lactamase gene
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
From December 2004 to March 2005, 27 Klebsiella pneumoniae clinical
isolates that were positive by the imipenem-EDTA double-disk synergy
test and that exhibited a single macrorestriction pattern were recovered
in two distinct Greek hospitals. The isolates carried a transferable
bla(VIM-t) metallo-beta-lactamase gene in a class I integron. Reverse
transcriptase PCR showed that the gene was similarly expressed in low-
and high-level carbapenem-resistant isolates, indicating the existence
of additional resistance mechanisms. The clonal spread of
VIM-1-producing K. pneumoniae strains in distinct regions where up to
now bla(VIM-2) and bla(VIM-4) alleles were common is worrisome.
Συγγραφείς:
Ikonomidis, A
Tokatlidou, D
Kristo, I
Sofianou, D and
Tsakris, A
Mantzana, P
Pournaras, S
Maniatis, AN
Περιοδικό:
Journal of Clinical Microbiology
Εκδότης:
AMER SOC MICROBIOLOGY
DOI:
10.1128/JCM.43.10.5344-5347.2005
