Τίτλος:
Statins: another class of antihypertensive agents?
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The assessment of global cardiovascular risk is an essential step in the
management of atherosclerotic disease prevention. Among the risk factors
to be addressed are hypertension and hyperlipidaemia; these commonly
coexist. A neutral or lipid-friendly antihypertensive agent is probably
useful in the presence of lipid abnormalities. Similarly, statins have
been shown to decrease cardiovascular risk in hypertensive patients.
There is also experimental and clinical evidence that statins have blood
pressure (BP)-lowering effects. In this review, we discuss the
beneficial effects of statins on BP, and provide an overview of the
underlying pathophysiology. We also consider the evidence justifying the
use of statins in the management of hypertensive patients.
Συγγραφείς:
Milionis, HJ
Liberopoulos, EN
Achimastos, A
Elisaf, MS and
Mikhailidis, DP
Περιοδικό:
Journal of Human Hypertension
Εκδότης:
Nature Publishing Group
Λέξεις-κλειδιά:
blood pressure; dyslipidaemia; pleiotropic effects; statins; vascular
disease
DOI:
10.1038/sj.jhh.1002001
