Τίτλος:
Update on the use of ciclosporin in immune-mediated dermatoses
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Immune-mediated dermatoses, such as psoriasis and atopic dermatitis,
affect a significant proportion of the population. Although most cases
are not life threatening, these diseases can have a profound effect on
the sufferer’s quality of life and that of their family. Systemic
therapy, such as ciclosporin, is often indicated for severe or
recalcitrant disease. The efficacy of ciclosporin in the treatment of
psoriasis and atopic dermatitis has been established and clinical data
also demonstrate its efficacy in treating less common but equally
challenging conditions such as pyoderma gangrenosum, lichen planus,
autoimmune bullous disease, recalcitrant chronic idiopathic urticaria
and chronic dermatitis of the hands and feet. The risk of potential
adverse events associated with ciclosporin is greatly reduced if current
treatment and monitoring guidelines are followed.
Συγγραφείς:
Griffiths, C. E. M.
Katsambas, A.
Dijkmans, B. A. C.
Finlay,
A. Y.
Ho, V. C.
Johnston, A.
Luger, T. A.
Mrowietz, U.
and Thestrup-Pedersen, K.
Περιοδικό:
British Journal of Dermatology
Λέξεις-κλειδιά:
calcineurin inhibitor; ciclosporin; dermatoses; efficacy;
immune-mediated; safety
DOI:
10.1111/j.1365-2133.2006.07343.x
