Περίληψη:
To investigate outcome and identify prognostic factors, we
retrospectively reviewed 24 consecutive patients with periosteal
chondrosarcomas. There were 17 males and seven females with a mean age
of 37.6 years (range, 15-73 years). The femur was involved in 12
patients, the proximal humerus in five, the tibia in two, and the distal
fibula, ilium, pubis, metatarsal, and rib in one patient each. The mean
greatest dimension of the lesions was 8.1 cm (range, 1.5-27 cm). Based
on the histologic pattern, there were 18 Grade 1 tumors and six Grade 2
tumors. All patients were treated surgically. Two patients had
intralesional excisions, five patients had marginal excisions, and 17
patients had wide resections. With a mean followup of 17 years (range,
28 months-47 years), seven of 24 patients (29%) had one or more local
recurrences. The 5-year local recurrence-free survival was less in
patients treated with intralesional or marginal excisions (25%) than
for patients treated with wide resections (93%). At the latest
followup, six of 24 patients (25%) had died of pulmonary metastases.
The overall 5-year metastasis-free survival was 83%. The 5-year
metastasis-free survival was less for patients with Grade 2 tumors
(50%) than for patients with Grade 1 tumors (94%).
Συγγραφείς:
Papagelopoulos, Panayiotis J.
Galanis, Evanthia C.
Mavrogenis,
Andreas F.
Savvidou, Olga D.
Bond, Jeffrey R.
Unni, Krishnan
K.
Sim, Franklin H.
