Τίτλος:
A novel technique to treat air leak following lobectomy: Intrapleural infusion of plasma
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: Persistent air leak following pulmonary lobectomy can be very difficult to treat and results in prolonged hospitalization. We aimed to evaluate the efficacy of a new method of postoperative air leak management using intrapleurally infused fresh frozen plasma via the chest tube. Material/Methods: Between June 2008 and June 2014, we retrospectively reviewed 98 consecutive patients who underwent lobectomy for lung cancer and postoperatively developed persistent air leak treated with intrapleural instillation of fresh frozen plasma. Results: The study identified 89 men and 9 women, with a median age of 65.5 years (range 48–77 years), with persistent postoperative air leak. Intrapleural infusion of fresh frozen plasma was successful in stopping air leaks in 90 patients (92%) within 24 hours, and in 96 patients (98%) within 48 hours, following resumption of the procedure. In the remaining 2, air leak ceased at 14 and 19 days. Conclusions: Intrapleural infusion of fresh frozen plasma is a safe, inexpensive, and remarkably effective method for treatment of persistent air leak following lobectomy for lung cancer. © Med Sci Monit, 2016.
Συγγραφείς:
Konstantinou, F.
Potaris, K.
Syrigos, K.N.
Tsipas, P.
Karagkiouzis, G.
Konstantinou, M.
Περιοδικό:
Medical science monitor: international medical journal of experimental and clinical research
Εκδότης:
International Scientific Literature Inc
Λέξεις-κλειδιά:
fresh frozen plasma, adjuvant therapy; adult; aged; Article; body position; bronchopleural fistula; chest tube; comorbidity; female; follow up; human; lung cancer; lung lobectomy; major clinical study; male; persistent air leak; pleura cavity; pleurodesis; postoperative complication; retrospective study; risk factor; smoking; surgical anatomy; thorax radiography; blood transfusion; freezing; Lung Neoplasms; middle aged; plasma; pneumothorax; Postoperative Complications; procedures; thorax surgery, Aged; Blood Transfusion; Chest Tubes; Female; Freezing; Humans; Lung Neoplasms; Male; Middle Aged; Plasma; Pneumothorax; Postoperative Complications; Retrospective Studies; Thoracic Surgical Procedures