Τίτλος:
Extranodal NK/T Cell Lymphoma, Nasal Type with Palatal Involvement: A Rare Case Report and Literature Review
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
T-cell lymphomas are infrequently encountered in the head and neck area, with the most common subtype being Extranodal NK/T cell lymphoma, nasal type (ENKTL-NT). ENKTL-NT shows a predilection for midline facial structures presenting with ulcerative destructive lesions, whereas palatal involvement is one of the most prominent signs from the oral cavity. Herein, we describe a case of a 76-year-old Greek man with nasal obstruction and an extensive painful necrotic ulcer with ragged borders on the left distal portion of the soft palate and palatine tonsil of 4-months duration. After an initial non-diagnostic biopsy from the nasopharynx, a second incisional biopsy from the palatal lesions was performed. Histopathology was suggestive of an angiocentric lymphoproliferative neoplasm and immunohistochemical examination and in situ hybridization for EBV RNA led to a final diagnosis of ENKTL-NT. The patient was placed under combined chemotherapy and radiotherapy and no recurrence has been noted. Additionally, a retrospective review of the cases in the English literature with an established diagnosis of ENTKL-NT between 2000 and 2019, based on the latest WHO classification of Head and Neck tumors, is performed. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
Συγγραφείς:
Andreou, A.
Thermos, G.
Sklavounou-Andrikopoulou, A.
Περιοδικό:
JOURNAL OF HEAD AND NECK PATHOLOGY
Λέξεις-κλειδιά:
aged; case report; human; male; NK T cell lymphoma; palatine tonsil; pathology; soft palate, Aged; Humans; Lymphoma, Extranodal NK-T-Cell; Male; Palate, Soft; Palatine Tonsil
DOI:
10.1007/s12105-020-01182-8
