Περίληψη:
For critically ill patients with coronavirus disease 2019 (COVID-19) who require intensive care unit (ICU) admission, extremely high mortality rates (even 97%) have been reported. We hypothesized that overburdened hospital resources by the extent of the pandemic rather than the disease per se might play an important role on unfavorable prognosis. We sought to determine the outcome of such patients admitted to the general ICUs of a hospital with sufficient resources. We performed a prospective observational study of adult patients with COVID-19 consecutively admitted to COVID—designated ICUs at Evangelismos Hospital, Athens, Greece. Among 50 patients, ICU and hospital mortality was 32% (16/50). Median PaO2 /FiO2 was 121 mmHg (interquartile range (IQR), 86–171 mmHg) and most patients had moderate or severe acute respiratory distress syndrome (ARDS). Hospital resources may be an important aspect of mortality rates, since severely ill COVID-19 patients with moderate and severe ARDS may have understandable mortality, provided that they are admitted to general ICUs without limitations on hospital resources. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
Συγγραφείς:
Routsi, C.
Magira, E.
Kokkoris, S.
Siembos, I.
Vrettou, C.
Zervakis, D.
Ischaki, E.
Malahias, S.
Sigala, I.
Asimakos, A.
Daidou, T.
Kaltsas, P.
Douka, E.
Sotiriou, A.
Markaki, V.
Temberikidis, P.
Koroneos, A.
Politis, P.
Mastora, Z.
Dima, E.
Tsoutsouras, T.
Papahatzakis, I.
Gioni, P.
Strilakou, A.
Maragouti, A.
Mizi, E.
Kanavou, A.
Sarri, A.
Gavrielatou, E.
Mentzelopoulos, S.
Kalomenidis, I.
Papastamopoulos, V.
Kotanidou, A.
Zakynthinos, S.
Λέξεις-κλειδιά:
azithromycin; glucocorticoid; hydroxychloroquine; lactic acid; lopinavir plus ritonavir; neuromuscular blocking agent; noradrenalin; remdesivir; troponin T, Acinetobacter baumannii; adult; adult respiratory distress syndrome; aged; APACHE; Article; artificial ventilation; atmospheric pressure; bacteremia; Caucasian; clinical article; comorbidity; computer assisted tomography; consciousness; continuous renal replacement therapy; coronavirus disease 2019; critically ill patient; deep vein thrombosis; diabetes mellitus; dyspnea; Enterococcus faecalis; female; follow up; Greece; hematologic malignancy; high flow nasal cannula therapy; hospital mortality; human; hypertension; hypoxemia; intensive care unit; intubation; invasive ventilation; kidney failure; Klebsiella pneumoniae; lactate blood level; lung infiltrate; male; mortality rate; nasopharyngeal swab; noninvasive ventilation; observational study; outcome assessment; oxygen therapy; patient referral; positive end expiratory pressure ventilation; positive pressure ventilation; practice guideline; prone position; prospective study; real time reverse transcription polymerase chain reaction; Sequential Organ Failure Assessment Score; shock; symptom; tertiary care center; tidal volume; tracheostomy
