Τίτλος:
Fetal subependymal giant cell astrocytoma: A case report and review of the literature
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: Subependymal giant cell astrocytomas (SEGAs) appear approximately in 10% of patients with tuberous sclerosis. These tumors are most commonly diagnosed in childhood and adolescence, with in utero diagnosed SEGAs being an extremely rare entity. Case Description: We present the case of a congenital SEGA detected in an antenatal ultrasound and further investigated with fetal magnetic resonance imaging (MRI) scans at 22 and 32 weeks of gestational age. At 9 days of age, the child underwent craniotomy and partial excision of the tumor, followed by a second more extensive operation 13 days later. The patient was subsequently administered mammalian target of rapamycin inhibitor (everolimus). Conclusion: In the latest follow-up MRI, at the age of two, the SEGA remained unchanged. Management of these tumors in neonates is challenging, mainly due to high morbidity and mortality of surgical treatment in these ages. © 2020 Scientific Scholar. All rights reserved.
Συγγραφείς:
Karagianni, A.
Karydakis, P.
Giakoumettis, D.
Nikas, I.
Sfakianos, G.
Themistocleous, M.
Περιοδικό:
Surgical Neurology International
Εκδότης:
SCIENTIFIC SCHOLAR LLC
Λέξεις-κλειδιά:
everolimus; glial fibrillary acidic protein; protein S 100; vigabatrin, angiomyolipoma; calcification; cancer patient; cancer surgery; case report; cell differentiation; choroid plexus papilloma; clinical article; craniotomy; electroencephalogram; female; fetus; focal epilepsy; follow up; gestational age; human; immunofluorescence; immunohistochemistry; macrophage; microglia; mortality; nuclear magnetic resonance imaging; pediatric patient; physical examination; postoperative period; priority journal; psammoma body; Review; subependymal giant cell astrocytoma; surgical patient; tuberous sclerosis; tumor volume
DOI:
10.25259/SNI_10_2019
