Τίτλος:
Influence of Supervised Disease Understanding and Diabetes Self-Management on Adherence to Oral Glucose-Lowering Treatment in Patients with Type 2 Diabetes
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Introduction: Systematic patient education has been reported to improve adherence to treatment, leading to better clinical outcomes. This cluster randomized real-world study investigated the effect of a systematic education program and telephone support on self-reported adherence to oral glucose-lowering treatment in patients with type 2 diabetes mellitus (T2DM). Methods: Centers were randomized (1:1) to provide either standard-of-care (control group) or standard-of-care along with the education program and telephone support (empowerment group). Adherence to treatment and satisfaction with treatment were assessed using the four-item Morisky Medication Adherence Scale (MMAS-4) and the Diabetes Treatment Satisfaction Questionnaire (DTSQ). The study population included 457 patients (258/199 male/female) with T2DM and non-optimal glycemic control, on oral antidiabetic treatment (age 62.7 [11.4]; disease duration 8.5 [6.5] years). Results: MMAS-4 high adherence rates for the control and empowerment groups were increased by 3.8% and 16.8% at 4 months (Breslow-Day test p = 0.04) and by 8.5% and 18.8% at 8 months of follow-up, respectively (Breslow-Day test p = 0.09), compared to baseline. Intense physical activity was increased in both control and empowerment groups by 2.3% and 13.9% at 4 months (Breslow-Day test p = 0.082) and by 4.0% and 22.5% at 8 months of follow-up (Breslow-Day test p < 0.001). Baseline mean (SD) HbA1c was significantly lower in the control group compared with the empowerment group [7.7% versus 8.0%, p = 0.001] and decreased in both groups at 4 months by 0.7% and 0.9%, respectively. The change from baseline in the mean DTSQ status score at 4 months was greater in the empowerment group, and the effect was sustained at 8 months (control group: 29.1, 30.5, and 30.9; empowerment group: 25.0, 28.7, and 29.4 at baseline, 4 and 8 months, respectively, p < 0.001). Conclusion: Systematic education combined with telephone support delivered by physicians might be associated with improvement in treatment adherence and treatment satisfaction in patients with T2DM. Funding: MSD, Greece. © 2019, The Author(s).
Συγγραφείς:
Doupis, J.
Alexandrides, T.
Elisaf, M.
Melidonis, A.
Bousboulas, S.
Thanopoulou, A.
Pagkalos, E.M.
Avramidis, I.
Pappas, A.
Arvaniti, E.
Karamousouli, E.
Voss, B.
Tentolouris, N.
Περιοδικό:
Diabetes Therapy
Εκδότης:
Springer Healthcare
Λέξεις-κλειδιά:
hemoglobin A1c; high density lipoprotein cholesterol; low density lipoprotein cholesterol; oral antidiabetic agent; triacylglycerol, adult; alcohol consumption; Article; assessment of humans; clinical assessment; comorbidity; controlled study; Diabetes Treatment Satisfaction Questionnaire; diabetic nephropathy; diabetic neuropathy; diabetic retinopathy; diastolic blood pressure; dyslipidemia; education program; empowerment; European Quality of Life 5 Dimensions questionnaire; European Quality of Life 5 Dimensions Visual Analogue Scale; female; four item Morisky Medication Adherence Scale; glucose blood level; glycemic control; health care quality; heart infarction; human; hypertension; ischemic heart disease; male; middle aged; non insulin dependent diabetes mellitus; patient compliance; patient education; patient satisfaction; patient-reported outcome; physical activity; prevalence; priority journal; randomized controlled trial; scoring system; self care; systolic blood pressure; telephone interview
DOI:
10.1007/s13300-019-0648-9
