Τίτλος:
Human Papillomavirus Vaccination and Infection in Young Sexual Minority Men: The P18 Cohort Study
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
We examined the prevalence of infection with human papillomavirus (HPV) and HIV in a cohort of young gay, bisexual, and other men who have sex with men [sexual minority men (SMM)]. HPV vaccination uptake was assessed; HIV antibody testing was performed and genetic testing for oral and anal HPV infection was undertaken. We examined both HPV vaccination and infection in relation to key demographic and structural variables. Participants (n = 486) were on average 23 years old; 70% identified as a member of a racial/ethnic minority group, and 7% identified as transgender females. Only 18.1% of the participants indicated having received the full dosage of HPV vaccination and 45.1% were unvaccinated. Slightly over half the participants (58.6%) were infected with HPV, with 58.1% testing positive for anal infection and 8.8% for oral infection. HIV seropositivity was associated with infection to oral HPV [adjusted odds ratio (AOR) = 4.03] and vaccine-preventable HPV, whereas both neighborhood-level poverty (AOR = 1.68) and HIV infection (AOR = 31.13) were associated with anal infection to HPV (AOR = 1.68). Prevalence of HPV infection is high among unvaccinated young SMM, despite the availability and eligibility for vaccination. HPV infection adds further health burden to these populations and is particularly concerning for those who are HIV positive as HIV infection increases the risk of developing HPV-related cancers. These findings underscore a missed prevention opportunity for an at-risk and underserved population and suggest the need for active strategies to increase HPV vaccination uptake in young SMM before the onset of sexual behavior. © Copyright 2019, Mary Ann Liebert, Inc., publishers 2019.
Συγγραφείς:
Halkitis, P.N.
Valera, P.
Loschiavo, C.E.
Goldstone, S.E.
Kanztanou, M.
Maiolatesi, A.J.
Ompad, D.C.
Greene, R.E.
Kapadia, F.
Περιοδικό:
AIDS Patient Care and STDs
Εκδότης:
MARY ANN LIEBERT INC PUBL
Λέξεις-κλειδιά:
mouthwash; Wart virus vaccine; Wart virus vaccine, adolescent; African American; Article; Caucasian; cohort analysis; female; Hispanic; human; Human immunodeficiency virus infection; major clinical study; male; mouth infection; multiplex polymerase chain reaction; papillomavirus infection; poverty; prospective study; sexual and gender minority; vaccination; adult; anal canal; bisexuality; ethnic group; genetics; Human immunodeficiency virus infection; isolation and purification; male homosexuality; minority group; Papillomaviridae; papillomavirus infection; prevalence; questionnaire; sexual and gender minority; vaccination; virology; young adult, Adult; Anal Canal; Bisexuality; Cohort Studies; Ethnic Groups; Female; HIV Infections; Homosexuality, Male; Humans; Male; Minority Groups; Papillomaviridae; Papillomavirus Infections; Papillomavirus Vaccines; Prevalence; Prospective Studies; Sexual and Gender Minorities; Surveys and Questionnaires; Vaccination; Young Adult
DOI:
10.1089/apc.2018.0276
