Τίτλος:
The Dilemma of Sex of Rearing: A Case of a 45,X/46,XY Neonate with Hydrocolpos
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: A rare disorder of sex development is 45,X/46,XY mosaicism, which is phenotypically very heterogenous, ranging from normal male (or female) to that of genital ambiguity of varying degrees. Case: We report a case of a neonate with 45,X/46,XY mosaicism and hydrocolpos, and we point out the dilemma and the difficulty in gender assignment. Summary and Conclusion: Gender assignment of cases with frank genital ambiguity is often difficult to be determined, because several factors have to be taken into consideration, such as genital appearance, anticipated urological and sexual function, capacity for future fertility, gonadal malignancy risk, and psychosocial factors. A multidisciplinary approach is definitely needed in the management of such cases. © 2018 North American Society for Pediatric and Adolescent Gynecology
Συγγραφείς:
Pesmatzoglou, M.
Kanaka-Gantenbein, C.
Dermentzoglou, V.
Voutetakis, A.
Nikaina, I.
Skiathitou, A.-V.
Siahanidou, T.
Περιοδικό:
Journal of Pediatric and Adolescent Gynecology
Εκδότης:
ELSEVIER SCIENCE INC 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
Λέξεις-κλειδιά:
45,X/46,XY mosaicism; ambiguous genitalia; Article; case report; clinical article; conservative treatment; echography; follow up; human; hydrocolpos; hypospadias; inguinal canal; micturition cystourethrography; newborn; orchidopexy; pelvis radiography; peripheral lymphocyte; priority journal; Turner syndrome; complication; female; gender identity; genital system; gonad; hydrocolpos; male; mixed gonadal dysgenesis; mosaicism; procedures; sexual development, Female; Gender Identity; Genitalia; Gonadal Dysgenesis, Mixed; Gonads; Humans; Hydrocolpos; Infant, Newborn; Male; Mosaicism; Sexual Development; Ultrasonography
DOI:
10.1016/j.jpag.2018.09.001
