Τίτλος:
Dose characterization of the new Bebig IsoSeed (R) I25.S17 using polymer
gel and MRI
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
A new, molybdenum core, I-125 interstitial brachytherapy seed is
marketed by Bebig GmbH (IsoSeed(R) 125.S17) and our group has performed
its Dosimetric characterization using Monte Carlo (MC) simulation and
Thermoluminescence dosimetry (TLD) as recommended by the AAPM TG-43U1
prior to the clinical implementation of new low-energy seeds. This work
presents the results of a supplementary experimental dosimetry study
performed using PABIG polymer gel and Magnetic Resonance Imaging (MRI).
One new I25.S17 seed and a commercially available, gold core. Bebig
IsoSeed(R) I25.S06 I-125 seed were positioned at two different locations
in a vial filled with water equivalent, PABIG-polymer gel. The gel with
the sources in place was M R scanned in 31) at various time intervals
after seed placement using a time efficient, 3D, dual echo Turbo Spin
Echo pulse sequence. The consensus dosimetry parameters published in the
TG-43U1 for the I25.S06 seed were used to derive the gel response
calibration curve for each scanning session. The calibration data were
then used to provide dosimetry results for the new I25.S17 seed.
Experimental results for the new seed in the form of dose distributions
as well as dosimetric quantities in the prevalent TG-43 dosimetric
formalism were found to be in close agreement with corresponding MC and
TLD results. This finding suggests that the polymer gel-MRI method could
at least play a supplementary role to TLD dosimetry in the dose
characterization of low energy/low dose rate brachytherapy sources,
especially in view of its potential for measurements with a fine spatial
resolution down to short distances which are inhibitory to conventional
experimental techniques. (c) 2006 Elsevier B.V. All rights reserved.
Συγγραφείς:
Pantelis, Evaggelos
Baltas, Dimos
Georgiou, Evaggelos and
Karaiskose, Pantelis
Lymperopoulou, Georgia
Papagiannis,
Panagiotis
Sakelliou, Loukas
Seimenis, Ioannis
Stilliaris,
Efstathios
Περιοδικό:
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION
A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
Εκδότης:
ELSEVIER SCIENCE BV
Λέξεις-κλειδιά:
polymer gel; MRI; dosimetry; brachytherapy
DOI:
10.1016/j.nima.2006.08.139
