Τίτλος:
Diverse types of epineural conduits for bridging short nerve defects. An
experimental study in the rabbit
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
In this study the process of peripheral nerve regeneration through an
epineural flap conduit was examined using four groups of 126 New Zealand
rabbits. There were three study groups (AT B, and C) and 1 control group
(D). A 10-mm long sciatic nerve defect was bridged either with 3
variations of an epineural flap (Groups A, BIT and C) or with a nerve
autograft (Group D). Animals from all groups were examined 21, 42, and
91 days postoperatively to evaluate nerve regeneration employing light
microscopy and immunocytochemistry. Nerve regeneration was studied in
transverse sections at 3, 6, and 9 mm from the proximal stump. The
gastrocnemius muscle contractility was also examined prior to euthanasia
at 91 days postsurgery in all groups using electromyography.
Immunohistochemical, histochemical and functional evaluation showed the
presence of nerve regeneration resembling the control group D,
especially in group A, where an advancement epineural flap was used. In
this experimental model an epineural flap can be used to bridge a nerve
defect successfully. (c) 2007 Wiley-Liss, Inc.
Συγγραφείς:
Ignatiadis, Ioannis A.
Yiannakopoulos, Christos K.
Barbitsioti,
Antonia D.
Avram, Adrian M.
Patralexis, Haralambos G. and
Tsolakis, Charilaos K.
Papalois, Apostolos E.
Xenakis, Theodoros
H.
Beris, Alexandros E.
Soucacos, Panayiotis N.
