Τίτλος:
Stiff person syndrome: avoiding misdiagnosis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Stiff person syndrome (SPS) is a rare neurological disorder
characterised by muscular rigidity and superimposed spasms of the trunk
and limbs that may be precipitated by voluntary movements and unexpected
tactile, auditory or emotional stimulation. The high prevalence of
autoantibodies against glutamic acid decarboxylase (antiGAD) in both
serum and cerebrospinal fluid, as well as the frequent association of
SPS with other autoimmune disorders, suggest an autoimmune pathogenesis.
SPS is frequently misdiagnosed as axial dystonia or psychogenic movement
disorder. We report a patient with SPS in order to emphasise the reasons
for this common misdiagnosis.
Συγγραφείς:
Andreadou, E.
Kattoulas, E.
Sfagos, C.
Vassilopoulos, D.
Περιοδικό:
Neurological Sciences
Εκδότης:
SPRINGER-VERLAG ITALIA SRL
Λέξεις-κλειδιά:
movement disorders; Stiff person syndrome; anti-GAD antibodies
DOI:
10.1007/s10072-007-0745-9
