Τίτλος:
Human papillomavirus assay in genital warts - correlation with symptoms
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Our purpose was to investigate the human papillomavirus (HPV) type
distribution using the Hybrid Capture 2 (HC2) Microplate assay in males.
We tested a urethral swab from 550 HIV-negative males with genital warts
and 64 HIV-negative males clinically free of genital warts, partners of
HPV-infected females, using the HC2 Microplate assay. A perianal swab
was also obtained from patients with perianal warts. In the first group,
HPV DNA of any type was detected in 280 (50.9%) patients. Relatively
few patients with urethral or perianal warts demonstrated a negative
test (both P < 0.0001). Low-risk types were commoner, accounting for
60.0% of the HPV cases, high/intermediate-risk types accounted for
23.6%, while 46 men (116.4%) were infected with both types. Of 13
subjects (20.3%) of the second group who tested positive for HPV DNA,
61.5% were infected by low-risk types, 23.1% by high/intermediate-risk
types and 15.4% had a dual infection. In conclusion, male partners of
infected females and males with genital warts are predominantly infected
by low-risk HPV types, but a substantial proportion is also or only
affected by high-risk types.
Συγγραφείς:
Hadjivassiliou, Maria
Stefanaki, Christina
Nicolaidou, Electra
and Bethimoutis, George
Anyfantakis, Vassilios
Caroni, Chrysseis
and Katsambas, Andreas
Περιοδικό:
International Journal of STD & AIDS
Εκδότης:
SAGE Publications Ltd
Λέξεις-κλειδιά:
human papillomavirus; high-risk HPV; low-risk HPV; genital warts;
cervical cancer; Hybrid Capture II Assay
DOI:
10.1258/095646207780749574
