Τίτλος:
Abdominal desmoid tumors
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Desmoid tumors are rare, benign, fibromatous lesions that are the result
of abnormal proliferation of myofibroblasts. Desmoid tumors can be
classified as extra-abdominal and abdominal. Abdominal desmoid tumors
are either superficial or intraabdominal. These tumors are associated
with a high recurrence rates, even if their microscopic characters
indicate a benign disease; their biologic behavior often indicates
rather a “malignant” disease, which can cause even the death.
Intraabdominal desmoid tumors can engulf surrounding viscera and
vessels, thereby greatly complicating their surgical treatment.
Management is multidisciplinary. Simple observation is a reasonable
management option for asymptomatic patients; spontaneous regression of
these tumors may be observed. Complete excision is the treatment of
choice for tumors causing symptoms or complications. Surgery should be
minimized as much as feasible, while at the same time achieving free
margins. Adjuvant therapy should be considered in selected cases; the
role of other management options (including gene transfer therapy) is
currently under intensive investigation. (c) 2007 Elsevier Ltd. All
rights reserved.
Συγγραφείς:
Sakorafas, George H.
Nissotakis, Christos
Peros, George
Περιοδικό:
SURGICAL ONCOLOGY-OXFORD
Εκδότης:
Elsevier Sci Ltd, Exeter, United Kingdom
Λέξεις-κλειδιά:
abdomen; desmoid; neoplasms; surgery
DOI:
10.1016/j.suronc.2007.07.009
