Τίτλος:
Venous thromboembolism after esophagectomy for cancer: a systematic review of the literature to evaluate incidence, risk factors, and prophylaxis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose: Although esophagectomy remains the preferred treatment for esophageal cancer, it is still associated with a number of complications, including post-operative venous thromboembolism (VTE). The aim of this study was to summarize the reported incidence of VTE after esophagectomy, its risk factors, and prevention strategies. Methods: We conducted a systematic search of the literature in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results: Fourteen studies met our inclusion criteria and were selected in the present review. Overall, we identified 9768 patients who underwent esophagectomy, with a post-operative VTE rate of 4% (440 patients). The reported risk factors for VTE included advanced age, American Society of Anesthesiologists (ASA) class III or IV, a history of cardiovascular or pulmonary disease, and the implementation of preoperative chemo-radiotherapy. Postoperative acute respiratory distress syndrome was also associated with VTE. No universally applied prevention strategies for VTE after esophagectomy were identified in the literature. Conclusions: Despite advances in perioperative care, VTE after esophagectomy still represents a source of morbidity for about 4% of patients. Low molecular weight heparin is suggested as the routine standard prophylactic regimen after esophageal cancer surgery. © 2021, Springer Nature Singapore Pte Ltd.
Συγγραφείς:
Theochari, N.A.
Theochari, C.A.
Kokkinidis, D.G.
Kechagias, A.
Lyros, O.
Giannopoulos, S.
Mantziari, S.
Schizas, D.
Περιοδικό:
Cataract & Refractive Surgery Today
Λέξεις-κλειδιά:
adverse event; aged; esophagus resection; esophagus tumor; female; human; incidence; male; middle aged; postoperative complication; risk factor; venous thromboembolism, Aged; Esophageal Neoplasms; Esophagectomy; Female; Humans; Incidence; Male; Middle Aged; Postoperative Complications; Risk Factors; Venous Thromboembolism
DOI:
10.1007/s00595-021-02260-2
