Τίτλος:
Hypertensive crisis and pulmonary edema following rituximab-induced anaphylaxis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Rituximab is a monoclonal antibody against the protein CD20. Various lymphomas as well as non-malignant immune disorders are treated with this antibody. Hypersensitivity reactions associated with the use of rituximab include urticaria, hypotension, chest tightness, vomiting, oxygen desaturation and bronchospasm. A very uncommon case of hypertensive crisis and pulmonary edema following rituximab-induced hypersensitivity reaction in an 80-year-old man receiving rituximab for non-Hodgkin lymphoma is reported. Anaphylaxis manifesting as coronary vasospasm following drug treatment, including rituximab, could be proved a serious condition in patients who need specific treatment. In these patients desensitization protocols seem to be mandatory.
Συγγραφείς:
Brili, S.
Bei, E.
Kounis, N.G.
Chrysohoou, C.
Antoniou, C.-K.
Kontopidou, F.
Bonfanti, L.
Cervellin, G.
Tousoulis, D.T.
Tsioufis, C.
Περιοδικό:
Acta bio-medica : Atenei Parmensis
Λέξεις-κλειδιά:
antineoplastic agent; monoclonal antibody; rituximab, anaphylaxis; case report; human; lung edema; male; nonhodgkin lymphoma; very elderly, Aged, 80 and over; Anaphylaxis; Antibodies, Monoclonal; Antineoplastic Agents; Humans; Lymphoma, Non-Hodgkin; Male; Pulmonary Edema; Rituximab
DOI:
10.23750/abm.v92iS1.11120
