Τίτλος:
Unfractionated heparin reduces hepcidin levels in critically ill patients
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
A strong anti-hepcidin activity has been observed in heparins. Mean hepcidin levels were significantly reduced compared to baseline, following the first day of unfractionated heparin administration in critically patients. Heparin displayed a strong independent negative association with hepcidin. These results may lead to future treatment methods of forms of anaemia characterised by hepcidin excess, common among the critically ill. © 2021 Royal Australasian College of Physicians
Συγγραφείς:
Vagionas, D.
Politou, M.
Kompoti, M.
Papadakis, D.-D.
Kostakou, E.
Theodoulou, D.
Kaniaris, E.
Rovina, N.
Koutsoukou, A.
Vasileiadis, I.
Περιοδικό:
Internal Medicine Journal
Εκδότης:
John Wiley and Sons Inc
Λέξεις-κλειδιά:
C reactive protein; creatinine; heparin; hepcidin; heparin; hepcidin, aged; APACHE; Article; biochemistry; blood sampling; chemiluminescence immunoassay; chemiluminescent microparticle immunoassay; chronic obstructive lung disease; clinical article; critically ill patient; disease exacerbation; dose response; drug dose increase; enzyme linked immunosorbent assay; female; heart failure; heart infarction; hospital admission; hospitalization; human; intensive care unit; limb ischemia; male; mortality; non invasive procedure; observational study; polyserositis; prospective study; renal replacement therapy; septic shock; treatment duration; anemia; critical illness, Anemia; Critical Illness; Heparin; Hepcidins; Humans
