Τίτλος:
Performance of breast lesion excision system (BLES) in complete removal of papillomas presented mammographically as groups of calcifications
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objectives: To retrospectively assess the stereotactic one-pass BLES performance in excision of small groups of calcifications seen on mammogram that proved to be papillomas. Methods: Between January 2014 and January 2016, 37/400 cases (9.2%) of stereotactic BLES biopsies performed in our department due to suspicious calcifications proved to be papillomas. Lesions with atypia underwent surgical removal and lesions with no atypia were followed up for 2 years. BLES and surgical histology results, radiological removal and 2-years stability were statistically analysed to assess BLES performance in biopsy and excision of papillomas. Results: The mean mammographic size of papillomas was 6.54 mm (st dev = 3.85, range 2 mm−17 mm) and within the size excised by the BLES needle (20 mm). 4/37 cases (10.8%) showed atypia. BLES excision was achieved in 29/37 cases (78.4%); radiological removal based on post BLES mammogram was achieved in 25/29 cases (86.2%). In the remaining 8/37 cases the papillomas were seen at the ink of the specimens' margins; 3/8 cases showed residual calcifications on post-BLES mammogram. The BLES histology result of removal and the mammographic size of the papillomas were found to be statistically significant predictive factors of excision (p < 0,001, Fisher's exact test, Mann Whitney test). Follow up mammograms showed no change for a period of 2 years. Conclusion: BLES is a safe and accurate technique to biopsy papillomas with high success rates of excision which could potentially minimize the need of subsequent radiological or surgical excision. © 2019 Elsevier Inc.
Συγγραφείς:
Christou, A.
Koutoulidis, V.
Koulocheri, D.
Panourgias, E.
Nonni, A.
Zografos, C.G.
Zografos, G.C.
Περιοδικό:
Clinical Imaging
Εκδότης:
HANLEY & BELFUS-ELSEVIER INC
Λέξεις-κλειδιά:
Biomineralization; Biopsy; Bone; Histology; Mammography; Surgery; X ray screens, BLES; Breast; Breast lesion; Excision; Mammographic; Papillomas; Predictive factors; Surgical excision, Tumors, adult; aged; Article; breast biopsy; breast calcification; breast lesion; breast papilloma; breast surgery; cancer surgery; clinical effectiveness; clinical evaluation; diagnostic accuracy; follow up; human; human tissue; major clinical study; mammography; patient safety; priority journal; retrospective study; stereotactic biopsy; surgical margin; tumor volume; breast tumor; diagnostic imaging; female; image guided biopsy; mammography; middle aged; multiple cancer; papilloma; stereotactic procedure; treatment outcome, Adult; Aged; Breast Neoplasms; Female; Humans; Image-Guided Biopsy; Mammography; Margins of Excision; Middle Aged; Neoplasms, Multiple Primary; Papilloma; Retrospective Studies; Stereotaxic Techniques; Treatment Outcome
DOI:
10.1016/j.clinimag.2019.06.009
