Τίτλος:
Neonatal screening for congenital CMV infection stresses the importance of maternal nonprimary infection even in an area where prenatal serology testing is common
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Aim and Methods: Dried blood spots from 2149 newborns were examined to diagnose congenital cytomegalovirus (cCMV). Results: Prenatal CMV-IgG antibodies had been measured during prenatal care in 1287 (60.3%) of mothers and 980 (76.1%) of them were found seropositive. cCMV incidence was 0.47%. All newborns were asymptomatic; 9/10 were born post nonprimary maternal infection; two developed sensorineural hearing loss. Conclusions: In a country where prenatal CMV testing is common and therefore a false sense of control might prevail, nonprimary maternal infection should not be overlooked. Indeed, women of childbearing age should be educated on CMV prevention measures irrespectively to their serostatus. © 2017, © 2017 Informa UK Limited, trading as Taylor & Francis Group.
Συγγραφείς:
Papaevangelou, V.
Christoni, Z.
Vliora, C.
Kottaridi, C.
Fotiou, A.
Malamitsi-Puchner, A.
Mentis, A.
Karakitsos, P.
Syggelou, A.
Περιοδικό:
Journal of Maternal-Fetal and Neonatal Medicine
Εκδότης:
Taylor and Francis Ltd.
Λέξεις-κλειδιά:
Cytomegalovirus antibody; immunoglobulin G, adult; Article; asymptomatic infection; cohort analysis; congenital infection; controlled study; cytomegalovirus infection; dried blood spot testing; female; human; incidence; major clinical study; male; newborn; newborn screening; perception deafness; prenatal care; priority journal; serology; asymptomatic infection; case report; cytomegalovirus infection; Greece; pregnancy; prevalence, Adult; Asymptomatic Infections; Cohort Studies; Cytomegalovirus Infections; Female; Greece; Humans; Infant, Newborn; Pregnancy; Prevalence
DOI:
10.1080/14767058.2017.1416605
