Τίτλος:
Accuracy and efficacy of embryo transfer based on the previous measurement of cervical length and total uterine length
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose: Aim of the study was to examine the accuracy of embryo transfer based on the previous measurement of cervical length and total uterine length. Methods: The study has taken place in an academic-assisted reproduction clinic. 248 patients with infertility requiring IVF/ICSI treatment have been included. All patients underwent IVF/ICSI cycles with antagonist protocol and were treated with controlled ovarian stimulation using recombinant FSH (100–400 IU/day). On the day of oocyte retrieval, all patients were given vaginally natural micronized progesterone in a dose of 200 mg/tds. All patients had transvaginal ultrasound measurement of cervical length and endometrial cavity length prior to embryo transfer and measurement of embryo distance (intrauterine air bubbles) from fundal surface of uterine cavity and internal cervical os immediately after embryo transfer. Embryo transfer was performed on days 2–3. Primary outcome was to estimate the accuracy of embryo transfer based on the measurement of the embryo distance from middle of uterine cavity after embryo transfer and secondary outcome was to assess the effect of embryo distance from uterine fundus and internal cervical os to clinical pregnancy rate. Results: The clinical pregnancy rate was 42.7%. The mean embryo distance from the middle of endometrial cavity was 0.48 ± 0.02 cm, the mean embryo distance from the uterine fundus was 0.88 ± 0.32 cm, and from the internal cervical os was 1.67 ± 0.45 cm. Multiple regression analysis showed that the embryo distance from middle of cavity was related to endometrial cavity length and to the embryo distance from the fundus and it was not related to Cx length, total uterine length, embryo distance from internal Cx os, and embryo transfer length. Conclusions: Embryo transfer with the previous measurement of total uterine length and estimation of embryo transfer length can be performed with very good accuracy by a single operator. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature.
Συγγραφείς:
Bakas, P.
Simopoulou, M.
Giner, M.
Tzanakaki, D.
Deligeoroglou, E.
Περιοδικό:
Archives of Gynecology and Obstetrics
Λέξεις-κλειδιά:
chorionic gonadotropin; ganirelix; progesterone; recombinant chorionic gonadotropin; recombinant follitropin, adult; Article; cervical length measurement; controlled study; embryo; embryo transfer; endometrium; female; female infertility; human; in vitro fertilization; intracytoplasmic sperm injection; major clinical study; measurement accuracy; oocyte; ovary; pregnancy; regression analysis; transvaginal echography; uterine cervix; uterine fundus; uterus; diagnostic imaging; echography; embryo transfer; procedures; uterus, Adult; Embryo Transfer; Female; Fertilization in Vitro; Humans; Pregnancy; Ultrasonography; Uterus
DOI:
10.1007/s00404-018-4971-6
