Τίτλος:
Giant cell tumor of soft tissue: A rare entity
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Giant cell tumor (GCT) of the soft tissue (GCT-ST) is a rare, unusual primary soft tissue tumor that is completely distinct from, and should not be confused with, any giant cell-rich tumor of bone or soft tissue. Currently, GCT-ST is included in the group of so-called fibrohistiocytic tumors of intermediate (borderline) malignancy. The most common symptom is a painless, slowgrowing mass in a superficial location. Computed tomography and magnetic resonance imaging show a solid, nonhomogeneous, frequently hemorrhagic mass. Differential diagnosis is broad and should include benign and malignant entities. The treatment and excision margins of GCT-ST are controversial. Incomplete surgical excision is usually followed by local recurrence. Biological behavior is unpredictable. Giant cell tumor of the soft tissue has shown a lower mean local recurrence rate compared to GCT of bone but has a higher metastatic and death rate. Therefore, close clinical follow-up is recommended. Copyright © 2019 SLACK Incorporated.
Συγγραφείς:
Mavrogenis, A.F.
Tsukamoto, S.
Antoniadou, T.
Righi, A.
Errani, C.
Περιοδικό:
Orthopedic Reviews
Εκδότης:
SLACK Incorporated
Λέξεις-κλειδιά:
benign neoplasm; biological activity; cancer radiotherapy; cancer surgery; cancer therapy; case study; clinical feature; computer assisted tomography; differential diagnosis; distant metastasis; genetics; giant cell tumor; histology; histopathology; human; immunophenotyping; lung metastasis; malignant neoplasm; mortality rate; nuclear magnetic resonance imaging; Review; skin defect; soft tissue; soft tissue tumor; surgical margin; tumor localization; tumor recurrence; tumor volume; giant cell tumor; orthopedic surgery; pathology; procedures; soft tissue tumor, Giant Cell Tumors; Humans; Neoplasm Recurrence, Local; Orthopedic Procedures; Soft Tissue Neoplasms
DOI:
10.3928/01477447-20190624-04
