Τίτλος:
Nepafenac ophthalmic suspension 0.3% for the management of ocular pain after photorefractive keratectomy
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
PURPOSE: To investigate the effect of nepafenac 0.3% in a once daily dosage regarding pain and healing after photorefractive keratectomy (PRK). METHODS: This was a prospective, comparative, contralateral randomized study of 35 patients undergoing PRK for the correction of low to moderate myopia and myopic astigmatism. After randomization, patients received nepafenac 0.3% ophthalmic suspension once daily in one eye (nepafenac 0.3% group) and nepafenac 0.1% ophthalmic suspension three times a day in the other eye (nepafenac 0.1% group) until the second postoperative day. Pain was evaluated every 2 hours on the day of the operation and then once daily using a scale ranging from 0 to 4. Patients were then examined at 2 weeks and 1, 3, 6, and 12 postoperative months. Visual acuity and subepithelial haze were also assessed. RESULTS: No differences were detected between groups in pain scores, subepithelial haze scores, or visual acuity. Refractive predictability was also similar. CONCLUSIONS: Nepafenac 0.3% ophthalmic suspension in a daily regimen after PRK seems to be an effective treatment for pain and ocular discomfort with effects similar to the 0.1% suspension. © 2018 Slack Incorporated. All rights reserved.
Συγγραφείς:
Kontadakis, G.A.
Chronopoulou, K.G.
Tsopouridou, R.
Tabibian, D.
Kymionis, G.D.
Περιοδικό:
Journal of Refractive Surgery
Εκδότης:
SLACK Incorporated
Λέξεις-κλειδιά:
nepafenac; benzeneacetamide derivative; eye drops; nepafenac; nonsteroid antiinflammatory agent; phenylacetic acid derivative, adult; Article; astigmatism; clinical article; controlled study; eye pain; female; haze; healing; human; male; myopia; pain assessment; photorefractive keratectomy; postoperative analgesia; postoperative pain; priority journal; prospective study; randomized controlled trial; suspension; treatment outcome; visual acuity; comparative study; excimer laser; eye pain; pain measurement; postoperative pain; procedures; therapeutic use; wound healing; young adult, Adult; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism; Benzeneacetamides; Eye Pain; Female; Humans; Lasers, Excimer; Male; Myopia; Ophthalmic Solutions; Pain Measurement; Pain, Postoperative; Phenylacetates; Photorefractive Keratectomy; Prospective Studies; Suspensions; Visual Acuity; Wound Healing; Young Adult
DOI:
10.3928/1081597X-20180123-03
