Depressive symptomatology in relation to 10-year (2004-2014) acute coronary syndrome incidence; the moderating role of diet and financial status

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3124445 17 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Depressive symptomatology in relation to 10-year (2004-2014) acute coronary syndrome incidence; the moderating role of diet and financial status
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: The association between depression status and 10-year cardiovascular disease (CVD) incidence among acute coronary syndrome (ACS) patients, in relation to nutritional and financial status, was evaluated. Methods: From October 2003 to September 2004, a sample of 2172 consecutive ACS patients from 6 Greek hospitals was enrolled. In 2013-14, the 10-year follow-up was performed. Depressive symptoms were evaluated using the validated CES-D score (range 0-60). Adherence to Mediterranean diet was assessed through MedDietScore (range 0-55) and financial status was determined by the annual income. Results: Ranking from the 1st to 3rd CES-D tertile, recurrent fatal/non fatal ACS rates were 33%, 37% and 42%, respectively (p = 0.006). Multiple logistic regression models revealed an adverse association of severe depression status (i.e. 3rd tertile) compared to no depression (i.e. 1st tertile) [odds ratio (OR) = 1.31, 95% confidence interval (95% CI) 1.01, 1.69]. When controlling for financial status, the relationship between depression and ACS prognosis remained marginally significant; while subgroup analysis revealed that only patients with low/moderate income were negatively affected [OR = 1.36, 95% CI 0.98, 1.88]. Further stratified analysis, by MedDietScore group, was applied; the above association remained significant only in patients with low compliance to this dietary pattern [OR = 1.68, 95% CI 1.10, 2.18]. Conclusions: ACS coexisting with severe depression status seems to result in adverse disease outcomes while financial status and Mediterranean diet are proposed as potential moderators. Public health programs should focus on vulnerable groups and minimize depressive symptoms through appropriate medical treatment and lifestyle interventions, so as to ameliorate the disease prognosis in clinical and community levels. © 2016 Elsevier Inc.
Έτος δημοσίευσης:
2016
Συγγραφείς:
Notara, V.
Panagiotakos, D.B.
Tsompanaki, E.
Kouvari, M.
Kogias, Y.
Papanagnou, G.
Antonoulas, A.
Stravopodis, P.
Zombolos, S.
Stergiouli, I.
Mantas, Y.
Babatsikou, F.
Pitsavos, C.
for the GREECS Study Investigators, Greece
Περιοδικό:
ISRN Preventive Medicine
Εκδότης:
Academic Press Inc.
Τόμος:
86
Σελίδες:
6-11
Λέξεις-κλειδιά:
acute coronary syndrome; adult; aged; Article; depression; disease duration; disease severity; fatality; female; human; incidence; lifestyle modification; lowest income group; major clinical study; male; Mediterranean diet; nutritional status; observational study; patient compliance; priority journal; prognosis; prospective study; social status; acute coronary syndrome; depression; diet; psychology; risk factor; socioeconomics; statistics and numerical data, Acute Coronary Syndrome; Aged; Depression; Diet; Diet, Mediterranean; Female; Humans; Incidence; Male; Prospective Studies; Risk Factors; Socioeconomic Factors
Επίσημο URL (Εκδότης):
DOI:
10.1016/j.ypmed.2016.01.009
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.