Τίτλος:
Sun lotion chemicals as endocrine disruptors
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Ultraviolet solar radiation is a well-known environmental health risk factor and the use of sun lotions is encouraged to achieve protection mainly from skin cancer. Sun lotions are cosmetic commercial products that combine active and inactive ingredients and many of these are associated with health problems, including allergic reactions and endocrine disorders. This review focuses on their ability to cause endocrine and reproductive impairments, with emphasis laid on the active ingredients (common and less common UV filters). In vitro and in vivo studies have demonstrated their ability to show oestrogenic/anti-oestrogenic and androgenic/ anti-androgenic activity. Many ingredients affect the oestrous cycle, spermatogenesis, sexual behaviour, fertility and other reproductive parameters in experimental animals. Their presence in aquatic environments may reveal a new emerging environmental hazard. © 2015, Hellenic Endocrine Society. All rights reserved.
Συγγραφείς:
Maipas, S.
Nicolopoulou-Stamati, P.
Περιοδικό:
Vitamins and Hormones
Εκδότης:
Hellenic Endocrine Society
Λέξεις-κλειδιά:
3 (4 methylbenzylidene)camphor; 3 benzylidene camphor; 4 aminobenzoic acid; 4 dimethylaminobenzoic acid 2 ethylhexyl ester; 4 hydroxybenzoic acid ester; 4 methoxycinnamic acid 2 ethylhexyl ester; amiloxate; avobenzone; bemotrizinol; benzocaine; benzophenone 1; benzophenone 2; bisoctrizole; cinoxate; dimeticone; dioxybenzone; ecamsule; endocrine disruptor; homosalate; meradimate; octisalate; octocrylene; octyl triazone; oxybenzone; phthalic acid; titanium dioxide; triethanolamine salicylate; unclassified drug; unindexed drug; uvinul A plus; zinc oxide; endocrine disruptor; sunscreen, androgenic activity; endocrine disease; estrogen activity; estrus cycle; exposure; fertility; gynecologic disease; health hazard; hormone action; human; in vitro study; in vivo study; lotion; male genital system disease; nonhuman; reproduction; reproductive health; Review; sexual behavior; skin penetration; solar radiation; spermatogenesis; ultraviolet radiation; animal; drug effects; risk factor, Animals; Endocrine Disruptors; Estrous Cycle; Fertility; Humans; Risk Factors; Sexual Behavior, Animal; Spermatogenesis; Sunscreening Agents
