Τίτλος:
The humanistic and economic burden of venous thromboembolism in cancer patients: A systematic review
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The objective of this study was to present evidence on the epidemiology, health outcomes and economic burden of cancer-related venous thromboembolism (VTE). Medline, Cochrane Central Register of Controlled Trials, Econlit, Science Direct, JSTOR, Oxford Journals and Cambridge Journals were searched. The systematic literature search was limited to manuscripts published from January 2000 to December 2012. On the basis of the literature, cancer patients experience between two-fold and 20-fold higher risk of developing VTE than noncancer patients. They are more likely to experience a VTE event during the first 3-6 months after cancer diagnosis. In addition, an increased risk of VTE in patients with distant metastases and certain types of cancer (i.e. pancreatic or lung) was revealed. VTE was found to be a leading cause of mortality in cancer patients. The annual average total cost for cancer patients with VTE was found to be almost 50% higher than that of cancer patients without VTE. Inpatient care costs accounted for more than 60% of total cost. The existing evidence assessed in the present review demonstrated the significant health and economic consequences of cancer-related VTE, which make a strong case for the importance of its proper and efficient prevention and management. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.
Συγγραφείς:
Kourlaba, G.
Relakis, J.
Mylonas, C.
Kapaki, V.
Kontodimas, S.
Holm, M.V.
Maniadakis, N.
Περιοδικό:
Blood Coagulation and Fibrinolysis
Εκδότης:
Lippincott Williams and Wilkins
Λέξεις-κλειδιά:
anticoagulant agent, acute leukemia; anticoagulant therapy; bile duct carcinoma; bleeding; cancer mortality; cancer patient; cancer survival; cardiovascular risk; colorectal cancer; distant metastasis; health care cost; health economics; high risk patient; hospital patient; hospitalization cost; human; length of stay; lung cancer; lung embolism; outcome assessment; overall survival; pancreas adenocarcinoma; pancreas cancer; prescription; priority journal; progression free survival; recurrence risk; Review; systematic review; venous thromboembolism; blood; case control study; cohort analysis; economics; Neoplasms; pathology; venous thromboembolism, Case-Control Studies; Case-Control Studies; Cohort Studies; Cohort Studies; Humans; Humans; Neoplasms; Neoplasms; Venous Thromboembolism; Venous Thromboembolism
DOI:
10.1097/MBC.0000000000000193
