Τίτλος:
Ossifying Fibromyxoid Tumor of the Retromolar Trigone: A Case Report and Systematic Review of the Literature
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Ossifying fibromyxoid tumor (OFMT) is a mesenchymal neoplasm of uncertain lineage and intermediate biologic behavior. Involvement of the head and neck area is infrequent (10% to 15%) and intraoral presentation is very rare. An OFMT developing in the retromolar trigone of a 13-year-old male is presented, along with a comprehensive review of oral OFMT cases. Among 12 oral OFMTs (including the present case), most patients were male (72.7%), with a mean age of 30.3 (13-67) years. The tumors generally appeared as painless masses of firm or hard consistency (mean diameter 27.7 mm), most commonly located in the soft tissues of the mandible (50%). Common microscopic features included ossification, lack of atypia or high mitotic activity, and immunohistochemical positivity for S100 (5/7), vimentin (6/6), GFAP (3/6), and SMA (2/6). Recurrence was reported only in one case. Further characterization of this rare entity is needed to increase our understanding of its distinct clinical and histopathologic features. © The Author(s) 2017.
Συγγραφείς:
Titsinides, S.
Nikitakis, N.G.
Tasoulas, J.
Daskalopoulos, A.
Goutzanis, L.
Sklavounou, A.
Περιοδικό:
International Journal of Surgical Pathology
Εκδότης:
SAGE Publications Inc.
Λέξεις-κλειδιά:
glial fibrillary acidic protein; protein S 100; smooth muscle actin; vimentin, adolescent; alveolar bone; anamnesis; cancer patient; cancer surgery; case report; clinical feature; cone beam computed tomography; connective tissue; excision; histopathology; human; immunohistochemistry; male; mandible; mandible tumor; microscopy; mitosis rate; mouth cavity; ossification; ossifying fibroma; ossifying fibromyxoid tumor of the retromolar trigone; panoramic radiography; priority journal; Review; soft tissue; soft tissue tumor; systematic review (topic); tumor localization; tumor recurrence; tumor volume; mouth tumor; ossifying fibroma; pathology, Adolescent; Fibroma, Ossifying; Humans; Male; Mouth Neoplasms
DOI:
10.1177/1066896917705197
