Τίτλος:
Circadian disruption of ICU patients: A review of pathways, expression, and interventions
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Intensive care unit patients typically exhibit pathologic wakefulness, poor quality of daytime sleep, nocturnal sleep fragmentation, and sleep patterns that feature the absence of slow wave sleep and rapid eye movement. This article offers a review of the existing literature examining circadian desynchronization in critically ill patients, highlighting contributing factors identified by scholars, and circadian abnormalities observed in these patients. It discusses potential implications for clinical practice and suggests avenues of future research. Elucidating the role of circadian rhythms in the management of critical illness can guide future chronotherapeutic approaches and optimize patient outcomes. © 2016 Elsevier Inc.
Συγγραφείς:
Korompeli, A.
Muurlink, O.
Kavrochorianou, N.
Katsoulas, T.
Fildissis, G.
Baltopoulos, G.
Περιοδικό:
Journal of Critical Care
Λέξεις-κλειδιά:
melatonin; melatonin, assisted ventilation; auditory stimulation; chronotherapy; circadian desynchronization; circadian rhythm; circadian rhythm sleep disorder; clinical practice; clinical research; cognition; critically ill patient; disease activity; drug therapy; human; immune system; light; nonhuman; nutritional support; pathologic wakefulness; patient care; Review; sleep; sleep quality; wakefulness; adverse effects; alarm monitor; artificial ventilation; critical illness; intensive care; intensive care unit; metabolism; noise; pathophysiology; REM sleep; sleep deprivation; sleep disorder, Chronobiology Disorders; Circadian Rhythm; Clinical Alarms; Critical Care; Critical Illness; Humans; Intensive Care Units; Light; Melatonin; Noise; Nutritional Support; Respiration, Artificial; Sleep; Sleep Deprivation; Sleep, REM
DOI:
10.1016/j.jcrc.2016.12.006
