Τίτλος:
Sagittal abdominal diameter may effectively predict future complications and increased mortality in intensive care unit patients with severe sepsis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose: To investigate whether increased visceral adipose tissue is a risk factor for increased morbidity and mortality in intensive care patients with severe sepsis. Materials and Methods: In this prospective cohort study, body mass index (BMI) and sagittal abdominal diameter (SAD) were measured in all patients with severe sepsis immediately after admission in the intensive care unit (ICU). The patients were followed up until death or discharge from ICU. The study's primary outcome measure was mortality until day 60 after admission, while secondary outcomes were morbidity, length of stay, and length of ventilation in ICU. Results: Of the 30 patients, 24 (80%) developed septic shock, 6 (20%) multiple organ dysfunction syndrome, 13 (43.3%) necessitated continuous venovenous hemodiafiltration, while 6 (20%) of them died. BMI and SAD had a statistically significant positive linear correlation with ICU length of stay ( P < .001) and length of ventilation ( P ≤ .001). However, only SAD was significantly correlated with the development of multiple organ dysfunction syndrome ( P = .033), the need for continuous venovenous hemodiafiltration ( P = .004), and death ( P = .033). Conclusion: An increased SAD may effectively predict future complications and increased mortality in intensive care unit patients with severe sepsis. © 2013 Elsevier Inc.
Συγγραφείς:
Chalkias, A.
Nitsotolis, T.
Papalexandrou, A.
Mikros, S.
Iacovidou, N.
Xanthos, T.
Περιοδικό:
Journal of Critical Care
Λέξεις-κλειδιά:
adult; adverse outcome; anthropometric parameters; article; assisted ventilation; body mass; clinical article; continuous hemodiafiltration; controlled study; disease severity; female; human; intensive care; intraabdominal fat; length of stay; male; morbidity; mortality; multiple organ failure; outcome assessment; prediction; prospective study; sagittal abdominal diameter; sepsis; septic shock; treatment duration, Intensive care; Morbidity; Mortality; Sagittal abdominal diameter; Severe sepsis, APACHE; Body Mass Index; Female; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Organ Dysfunction Scores; Predictive Value of Tests; Prospective Studies; Respiration, Artificial; Sagittal Abdominal Diameter; Sepsis
DOI:
10.1016/j.jcrc.2013.06.022
