Τίτλος:
The effect of laparoscopic sleeve gastrectomy on the antireflux mechanism: Can it be minimized?
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: Laparoscopic sleeve gastrectomy (LSG) is a promising procedure for the treatment of morbid obesity. The stomach is usually transected near the angle of His; hence, the lower esophageal sphincter (LES) may be affected with consequences on postoperative gastroesophageal reflux disease (GERD). The purpose of this study was to examine the effect of LSG on the LES and postoperative GERD. Methods: Severely obese asymptomatic patients submitted to LSG underwent esophageal manometry and GERD evaluation preoperatively and at least 6 weeks postoperatively. Data reviewed included patient demographics, manometric measurements, GERD symptoms, and pathology. Statistical analysis was performed by SPSS software. Results: Twelve male and eleven female patients participated in the study. Mean age was 38.5 ± 10.9 years, and initial body mass index was 47.9 ± 5.1 kg/m2. At follow-up examination, mean excess body mass index loss was 32.3 ± 12.7 %. The LES total and abdominal length increased significantly postoperatively, whereas the contraction amplitude in the lower esophagus decreased. There was an increase in reflux symptoms postoperatively (p < 0.009). The operating surgeon who mostly approximated the angle of His resulted in an increased abdominal LES length (p < 0.01). The presence of esophageal tissue in the specimen correlated with increased total GERD score (p < 0.05). Conclusions: LSG weakens the contraction amplitude of the lower esophagus, which may contribute to postoperative reflux deterioration. It also increases the total and the abdominal length of the LES, especially when the angle of His is mostly approximated. However, if this approximation leads to esophageal tissue excision, reflux is again aggravated. Thus, stapling too close to the angle of His should be done cautiously. © 2013 Springer Science+Business Media New York.
Συγγραφείς:
Kleidi, E.
Theodorou, D.
Albanopoulos, K.
Menenakos, E.
Karvelis, M.A.
Papailiou, J.
Stamou, K.
Zografos, G.
Katsaragakis, S.
Leandros, E.
Περιοδικό:
Surgical Endoscopy
Εκδότης:
Springer New York LLC
Λέξεις-κλειδιά:
adult; antireflux operation; article; body mass; clinical article; controlled study; disease severity; dysphagia; esophagus manometry; female; gastroesophageal reflux; heartburn; human; laparoscopic surgery; lower esophagus sphincter; male; morbid obesity; postoperative period; preoperative evaluation; priority journal; Roux Y anastomosis; sleeve gastrectomy; surgical technique; thorax pain, Adult; Esophageal Sphincter, Lower; Female; Follow-Up Studies; Gastrectomy; Gastroesophageal Reflux; Humans; Laparoscopy; Male; Manometry; Obesity, Morbid; Postoperative Period; Pressure; Prospective Studies; Treatment Outcome
DOI:
10.1007/s00464-013-3083-4
