Τίτλος:
Psychomotor development of children born after preimplantation genetic diagnosis and parental stress evaluation
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: The increasing number of children conceived following preimplantation genetic diagnosis (PGD) necessitates the evaluation of their motor and cognitive development. The primary study objective was to evaluate the physical, developmental, and neurological outcome of children born after PGD in Greece. In addition, the secondary study objective was to compare the stress levels regarding parental roles between parents of PGD children and those of naturally conceived children. Methods: A cross-sectional study design was applied. The study population consisted of 31 children (aged 2 months to 7.5 years) born after PGD analysis and their parents. The developmental evaluation of children included a detailed physical evaluation and cognitive assessment with the Bayley Scales of Infant Development. The parent stress index was applied to evaluate comparative parental stress levels between those parents of PGD children and those of naturally conceived healthy children. Results: High rates of caesarean deliveries, increased incidence of prematurity, multiples and low-birth weight were observed among the 31 PGD children. Overall, 24 of the 31 PGD children had cognitive skills within normal range [general developmental quotient (GDQ): 86-115], while 6 children had lower levels of cognitive skills (GDQ<85). With regard to parental stress, PGD parents reported lower levels of parenting stress as compared to parents of naturally conceived children (P<0.01). Conclusions: The enhanced frequency of poor cognitive and motor skills as well as low parental stress necessitates early detection and intervention for developmental delays among PGD children. © Children's Hospital, Zhejiang University School of Medicine, China and Springer-Verlag Berlin Heidelberg 2012.
Συγγραφείς:
Thomaidis, L.
Kitsiou-Tzeli, S.
Critselis, E.
Drandakis, H.
Touliatou, V.
Mantoudis, S.
Leze, E.
Destouni, A.
Traeger-Synodinos, J.
Kafetzis, D.
Kanavakis, E.
Περιοδικό:
World Journal of Pediatrics
Λέξεις-κλειδιά:
adult; article; Bayley Scales of Infant Development; cesarean section; child; child development; clinical article; clinical assessment; cognitive development; controlled study; cross-sectional study; female; genetic screening; Greece; human; infant; low birth weight; male; multiple pregnancy; newborn sepsis; parent; parental stress; physical development; preimplantation genetic diagnosis; prematurity; prenatal diagnosis; preschool child; psychologic assessment; psychomotor development; rating scale; school child; self report, Adult; Cesarean Section; Child; Cognition Disorders; Cross-Sectional Studies; Developmental Disabilities; Humans; Motor Skills; Parents; Preimplantation Diagnosis; Stress, Psychological
DOI:
10.1007/s12519-012-0374-0
