Τίτλος:
Commonest overgrowth syndromes
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Overgrowth syndromes, although rare, are diagnosed more frequently lately. Major progress, such as the identification of genetic causes, has recently enhanced the delineation of the characteristic and noncharacteristic manifestations, phenotype-genotype correlations and knowledge of the underlying pathophysiologic mechanisms. This review provides a summary of the most important overgrowth syndromes aiming to familiarize the treating physician with the cardinal clinical features involved in these syndromes that encompass overgrowth, but also have a variety of other clinical manifestations (neurologic, musculoskeletal, skin, and accompanying tumors). © 2012 Informa Healthcare USA, Inc.
Συγγραφείς:
Ekmektzoglou, K.
Demestiha, T.
Troupis, G.
Xanthos, T.
Περιοδικό:
Fetal and Pediatric Pathology
Λέξεις-κλειδιά:
angioosteohypertrophy syndrome; article; Bannayan Riley Ruvalcaba syndrome; Beckwith Wiedemann syndrome; clinical feature; fragile X syndrome; genotype; growth disorder; human; hyperplasia; multiple cancer; neurofibromatosis; osteochondroma; overgrowth syndrome; pathophysiology; perlman syndrome; phenotype; practice guideline; priority journal; Simpson Golabi Behmel syndrome; Sotos syndrome; weaver syndrome, Abnormalities, Multiple; Body Size; Growth Disorders; Humans; Hyperplasia; Syndrome
DOI:
10.3109/15513815.2011.650293
