Τίτλος:
Sonographic findings in severe fetomaternal transfusion
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The Fetal Medicine Practice, Athens, Greece Abstract Fetomaternal hemorrhage (FMH) or fetomaternal transfusion syndrome is the leakage of fetal red blood cells into the maternal circulation. Massive FMH can cause substantial fetal morbidity and mortality. Sonographic evidence of severe FMH syndrome includes fetal hydrops and other fetal anemia-related Wndings. The peak systolic velocity in the middle cerebral artery has extensively been used for the prediction of fetal anemia and for the timing of the Wrst intrauterine intravascular transfusion (IIVT). We present a case of severe FMH syndrome that was diagnosed during the 24th week of pregnancy. A total of eight IIVT were performed. The actual increase in the fetal Hb after each transfusion was much lower than the expected. At 27 weeks of gestation, sonographic evaluation revealed areas of echogenicity around the posterior horns of the lateral ventricles suggesting ischemic damage. Due to these Wndings, no further IIVTs were offered and the fetus died a week later. The management of fetal anemia caused by severe FMH is difficult, and the anemic fetuses do not respond well to serial IIVTs as the transfer of blood to the maternal circulation continues.
Συγγραφείς:
Sifakis, S.
Koukoura, O.
Konstantinidou, A.E.
Kikidi, K.
Prezerakou, M.
Kaminopetros, P.
Περιοδικό:
Archives of Gynecology and Obstetrics
Λέξεις-κλειδιά:
hemoglobin F; hemoglobin, adult; anemia; article; ascites; brain calcification; brain hemorrhage; brain ischemia; brain ventricle dilatation; case report; chorioamnionitis; cordocentesis; disease severity; Doppler flowmetry; female; fetomaternal transfusion; fetus; fetus death; fetus disease; fetus echography; fetus hydrops; gestational age; heart ventricle hypertrophy; hepatosplenomegaly; histology; human; interstitial nephritis; intrauterine blood transfusion; lung infiltrate; pericardial effusion; placenta disorder; pleura effusion; second trimester pregnancy; echography; fetomaternal transfusion; intrauterine blood transfusion; pregnancy; standard, Adult; Blood Transfusion, Intrauterine; Female; Fetal Death; Fetomaternal Transfusion; Fetus; Hemoglobins; Humans; Pregnancy
DOI:
10.1007/s00404-009-1123-z
