Τίτλος:
Serum Apoptotic Caspase Activity in Chronic Hepatitis C and Nonalcoholic Fatty Liver Disease
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Apoptotic caspases are substantially activated in liver and serum caspase activity has been suggested as a marker of early liver injury. To investigate whether serum levels of caspase-generated fragments of cytokeratin-18 are associated with the severity of histologic lesions in chronic hepatitis C virus (HCV) infection and nonalcoholic fatty liver disease (NAFLD). © 2010 Lippincott Williams & Wilkins, Inc.
Συγγραφείς:
Papatheodoridis, G.V.
Hadziyannis, E.
Tsochatzis, E.
Georgiou, A.
Kafiri, G.
Tiniakos, D.G.
Margariti, K.
Manolakopoulos, S.
Manesis, E.K.
Archimandritis, A.J.
Περιοδικό:
Journal of Clinical Gastroenterology
Λέξεις-κλειδιά:
caspase; cytokeratin 18, adult; apoptosis; article; controlled study; diagnostic accuracy; disease severity; female; hepatitis C; histology; human; liver biopsy; major clinical study; male; nonalcoholic fatty liver; priority journal; serum, Adolescent; Adult; Aged; Apoptosis; Biological Markers; Caspases; Diagnosis, Differential; Fatty Liver; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Keratin-18; Male; Middle Aged; Young Adult
DOI:
10.1097/MCG.0b013e3181c0945a
