Τίτλος:
Efficacy and cost-effectiveness of cell saving blood autotransfusion in adult lumbar fusion
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The objective of this study was to explore the use of cell saver blood autotransfusion in spinal surgery and to evaluate the efficacy and cost-effectiveness of cell saver blood autotransfusion during lumbar spine fusion in adults. Specific indications for the use of cell saver in adult lumbar fusion surgery have not yet been clearly determined. A total of 50 consecutive candidates for posterolateral fusion with internal fixation were prospectively randomized into either receiving perioperatively cell saving autotransfusion (Group A: 25 patients) or not (Group B: 25 patients). The use of cell saving technique did not exclude the use of allogenic blood transfusion. Surgical indications were spinal stenosis, spondylolisthesis, adolescent idiopathic scoliosis, degenerative scoliosis and fractures. Medical and financial data were recorded. A cost-analysis was performed. Patients in Group A received 880 ± 216 mL from cell saver and 175 ± 202 mL allogenic blood. The patients in Group B received 908 ± 244 mL allogenic blood. Blood volumes data collected were expressed in mean ± SD values. The cost of blood transfusion in Group A was 995 ±€447 per patient and 1220 ± 269 in Group B (P < 0.05). In elective lumbar fusion blood requirements can be satisfied with the use of autotransfusion. The use of cell saver appears to be useful and cost-effective during most elective lumbar fusions. © 2009 British Blood Transfusion Society.
Συγγραφείς:
Savvidou, C.
Chatziioannou, S.N.
Pilichou, A.
Pneumaticos, S.G.
Περιοδικό:
Transfusion Medicine
Λέξεις-κλειδιά:
adolescent; adult; aged; allotransplantation; article; blood autotransfusion; blood transfusion; blood volume; cell therapy; clinical article; clinical trial; controlled clinical trial; controlled study; cost benefit analysis; cost control; cost effectiveness analysis; female; human; idiopathic scoliosis; lumbar spine; male; osteosynthesis; prospective study; randomized controlled trial; spine fusion; spine surgery; vertebral canal stenosis, Adolescent; Adult; Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion, Autologous; Costs and Cost Analysis; Female; Humans; Male; Middle Aged; Spinal Diseases; Spinal Injuries
DOI:
10.1111/j.1365-3148.2009.00929.x