Τίτλος:
The effect of the type of intraperitoneally implanted prosthetic mesh on the systemic inflammatory response
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: The purpose of this study was to determine any differences in the systemic inflammatory response after the intraperitoneal implantation of three different types of polypropylene mesh. Methods: Thirty-two male New Zealand rabbits underwent a 6-cm midline incision and opening of the peritoneal cavity. The animals were randomly divided into four groups. In groups A, B, and C, there was an intraperitoneal placement of polypropylene mesh, titanium-coated polypropylene mesh, and composite polypropylene/e-PTFE mesh, respectively. Group D received a sham operation. Blood was sampled preoperatively and at 6, 24, 48, and 168 h postoperatively to measure white blood cell count (WBC), tumor necrosis factor-alpha (TNF-α), and malondialdehyde (MDA). Results: Statistically significant elevations of WBC, TNF-α and MDA were observed in all four groups at 6, 24, and 48 h postoperatively (P < 0.05). There were no statistically significant differences in WBC, TNFα, and MDA between groups A, B, and C at any time interval. However, a statistically significant elevation of WBC (P < 0.05) and TNFα (P < 0.05) was observed between each of the groups with mesh implantation and group D at 24 h postoperatively. Conclusion: Intraperitoneal mesh implantation induces mild systemic inflammatory response regardless of the type of implanted mesh. © Springer-Verlag 2008.
Συγγραφείς:
Chatzimavroudis, G.
Koutelidakis, I.
Papaziogas, B.
Tsaganos, T.
Koutoukas, P.
Giamarellos-Bourboulis, E.
Atmatzidis, S.
Atmatzidis, K.
Περιοδικό:
Revista Hispanoamericana de Hernia
Λέξεις-κλειδιά:
malonaldehyde; politef; polypropylene; tumor necrosis factor alpha, animal experiment; animal model; article; blood analysis; blood sampling; controlled study; leukocyte count; male; mesh sling; nonhuman; peritoneum; politef implant; postoperative period; priority journal; rabbit; surgical equipment; systemic inflammatory response syndrome, Animals; Hernia; Leukocyte Count; Malondialdehyde; Peritoneum; Polypropylenes; Rabbits; Random Allocation; Statistics, Nonparametric; Surgical Mesh; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha
DOI:
10.1007/s10029-007-0327-z
