Τίτλος:
The efficacy of Caelyx and Hyperthermia for anticancer treatment
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The efficacy of Hyperthermia and Caelyx as single modalities of therapy
in progressed and refractory cancer of different primary sites is well
known. Nevertheless, it remains question mark whether they can work
together to that direction. We have recently published a paper which
demonstrates some excellent results in treatment of recurrent breast
cancer with hyperthermia in conjunction with Caelyx and radiotherapy.
The mechanism of action of those different therapeutic options and a
review in literature are presented in this paper. Despite the limited
number of studies, they all show that the combined treatment is
effective and well tolerated. It would be interesting to mention another
treatment patent of cancer which can be done by a combination of
non-ionizing radiation and androgen deprivation. Also, combined therapy
for tumors and tumor metastases comprised administration of integrin
ligands and co-therapeutic agents have synergistic efficacy in isolated
organ perfusion. Finally, the treatment of solid tumors can be done by
glycolytic inhibitors.
Συγγραφείς:
Kouloulias, Vasilios E.
Koukourakis, Georgios V.
Petridis,
Aristides K.
Kouvaris, Ioannis
Gouliamos, Athanasios D.
Περιοδικό:
Recent Patents on Anti-Cancer Drug Discovery
Εκδότης:
BENTHAM SCIENCE PUBL LTD
Λέξεις-κλειδιά:
Hyperthermia; caelyx; efficacy; anticancer treatment
DOI:
10.2174/157489207782497208
