Τίτλος:
Pathological review of internal genitalia after anterior exenteration
for bladder cancer in women. Evaluating risk factors for female organ
involvement
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
To evaluate cancer involvement of internal female genitalia of patients
undergoing anterior exenteration for clinically organ confined
transitional cell carcinoma of the bladder, and identify potential
preoperative risk factors. Charts and anterior exenteration specimens
from 54 women with clinically organ confined transitional cell bladder
cancer were retrospectively reviewed. Emphasis was given to the presence
of internal genitalia involvement and or primary gynecologic pathology.
Unsuspected internal genitalia involvement was reported in only three
patients (5.7%). The vagina was involved in two cases (3.8%) while the
uterus in one (1.9%). In all cases involvement was due to direst
extension from bladder tumors of the base and dome respectively. No
preoperative variable could predict internal genitalia involvement in a
statistical significant manner. Benign pathology of the female
reproductive organs was observed in six patients and involved in all
cases the uterus (11.5%). Internal genitalia involvement after radical
cystectomy for TCC tumors of the bladder is rare (5.8%). Preoperative
risk factors could not be identified although all involved genitalia
were seen in tumors of the bladder dome and base. Therefore large
multi-institutional studies are needed in order to identify preoperative
risk factors for internal genitalia involvement in females with bladder
cancer.
Συγγραφείς:
Varkarakis, Ioannis M.
Pinggera, Germar
Antoniou, Nikolaos and
Constantinides, Kostas
Chrisofos, Michail
Deliveliotis,
Charalambos
Περιοδικό:
International Urology and Nephrology
Λέξεις-κλειδιά:
radical cystectomy; reproductive organs; female
DOI:
10.1007/s11255-006-9158-6
