Τίτλος:
Intake of vegetables, legumes, and fruit, and risk for all-cause,
cardiovascular, and cancer mortality in a European diabetic population
Περίληψη:
We examined the associations of intake of vegetables, legumes and fruit
with all-cause and cause-specific mortality in a population with
prevalent diabetes in Europe. A cohort of 10,449 participants with
self-reported diabetes within the European Prospective Investigation
into Cancer and Nutrition study was followed for a mean of 9 y. Intakes
of vegetables, legumes, and fruit were assessed at baseline between 1992
and 2000 using validated country-specific questionnaires. A total of
1346 deaths occurred. Multivariate relative risks (RR) for all-cause
mortality were estimated in Cox regression models and FIR for
cause-specific mortality were derived in a competing risk model. An
increment in intake of total vegetables, legumes, and fruit of 80 g/d
was associated with a RR of death from all causes of 0.94 [95% CI
0.90-0.98]. Analyzed separately, vegetables and legumes were associated
with a significantly reduced risk, whereas nonsignificant inverse
associations for fruit intake were observed. Cardiovascular disease
(CVD) mortality and mortality due to non-CVD/non-cancer causes were
significantly inversely associated with intake of total vegetables,
legumes, and fruit (RR 0.88 [95% CI 0.81-0.95] and 0.90
[0.82-0.99], respectively) but not cancer mortality 0.08
[0.99-1.17]). Intake of vegetables, legumes, and fruit was associated
with reduced risks of all-cause and CVD mortality in a diabetic
population. The findings support the current state of evidence from
general population studies that the protective potential of vegetable
and fruit intake is larger for CVD than for cancer and suggest that
diabetes patients may benefit from a diet high in vegetables and fruits.
Συγγραφείς:
Noethlings, Ute
Schulze, Matthias B.
Weikert, Cornelia and
Boeing, Heiner
van der Schouw, Yvonne T.
Bamia, Christina and
Benetou, Vasiliki
Lagiou, Pagona
Krogh, Vittorio
Beulens,
Joline W. J.
Peeters, Petra H. M.
Halkjaer, Jytte and
Tjonneland, Anne
Tumino, Rosario
Panico, Salvatore
Masala,
Giovanna
Clavel-Chapelon, Francoise
de Lauzon, Blandine and
Boutron-Ruault, Marie-Christine
Vercambre, Marie-Noel
Kaaks,
Rudolf
Linseisen, Jakob
Overvad, Kim
Arriola, Larraitz and
Ardanaz, Eva
Gonzalez, Carlos A.
Tormo, Marie-Jose
Bingham,
Sheila
Khaw, Kay-Tee
Key, Tim J. A.
Vineis, Paolo and
Riboli, Elio
Ferrari, Pietro
Boffetta, Paolo and
Bueno-de-Mesquita, H. Bas
van der A, Daphne L.
Berglund, Goeran
and Wirfalt, Elisabet
Hallmans, Goeran
Johansson, Ingegerd and
Lund, Eiliv
Trichopoulo, Antonia